Mosaic Health Solutions — MosaicRx by Nihit Gurram. Prevent prescribing cascades before they cause harm.
MosaicRx, by Mosaic Health Solutions, is a real-time medication risk prioritization layer at the moment of prescribing. Phenotype-driven, glass-box explainable, and designed for the clinician-in-the-loop.
Elevated anticholinergic burden
HighCumulative ACB score 7 across 3 active meds — associated with cognitive slowing & falls.
Prescribing cascade signal
WatchDiuretic started 14 days after NSAID initiation — temporal pattern consistent with cascade.
Fall-risk phenotype: high
HighOrthostatics + sedating load + recent gait change. Phenotype match 0.89.
The most expensive medication errors don't look like errors.
They look like new diseases — until a patient falls, becomes delirious, or lands in the ED. By then, the chain is invisible.
We help prevent the fall that leads to a $30K+ hospitalization.
Top 3 risks · why they matter · what's driving them.
MosaicRx isn't another alert. It's a prioritized, patient-specific read on what could go wrong in the next 90 days — delivered the moment a clinician opens the chart.
- Phenotype-specific, not population-generic
Risks are scored against the patient's longitudinal trajectory, not a static drug-drug table.
- Glass Box explainability
Every signal exposes its evidence trail: contributing meds, timing, and the questions worth reviewing.
- Clinician-in-the-loop, always
MosaicRx surfaces. The clinician decides. Nothing auto-prescribes, nothing auto-stops.
Cumulative ACB ≥ 3 in adults >75 is associated with cognitive decline, urinary retention, and falls. Patient's score: 7.
- →Is amitriptyline still needed for sleep, or can it be tapered?
- →Substitute oxybutynin with mirabegron?
Three steps. No new workflow.
Context capture
EHR data, longitudinal medication history, labs, and real-world inputs where available — assembled into a patient-specific picture.
Risk engine
Phenotype-aware models rank by relevance, not completeness. Built explicitly to avoid alert fatigue.
Glass Box output
Top 3 risks with evidence trace, contributing meds, timeline, and questions to review. Clinician decides.
Not an alert. Not a scribe. Not a polypharmacy calculator.
MosaicRx sits in a category of one: a prioritization layer at the prescribing moment, designed around clinical judgment.
Reduce complications. Protect margin under risk.
For risk-bearing groups and value-based systems, prevented complications are the line item. MosaicRx targets the high-cost, hard-to-see misses.
- Reduce medication-driven complications, LOS extension, and readmission risk.
- Improve financial performance within DRG-based reimbursement by reducing outlier cases.
- Strengthen quality and safety metrics with a defensible evidence trail.
One prevented fall.
The average fall-related hospitalization for an older adult exceeds $30K. A single prevented event can offset the annual cost of MosaicRx.
Illustrative only. Actual results depend on population, baseline, and workflow.
Pilot MosaicRx in a community clinic.
Designed for risk-bearing outpatient groups managing complex older adults. Start with a focused workflow — integration follows once value is proven.
- A clinical champion and 3–10 prescribing clinicians
- Synthetic or de-identified workflow for week 1 (no integration required)
- Defined patient cohort (e.g., 65+ with ≥5 active meds)
- Optional EHR integration scoped after pilot validation
- Cascade interception rate
- Insight acceptance rate
- Repeat use per clinician
- Time recovered per encounter
- Explainability engagement rate
The team building MosaicRx.
A clinician-aware, builder-first team backed by senior clinical and commercial advisors across Stanford, community medicine, and value-based care.
Operator-clinician translator. Builds at the intersection of value-based care, medication safety, and prescribing workflow.
Mathematical biology and clinical modeling. Translates phenotype-driven risk into rigorous, defensible signal.
Engineering leader. Built mission-critical civic tech at scale. Owns architecture, security, and the EHR integration path.
The questions clinical and economic buyers actually ask.
Request a demo or start a pilot conversation.
Tell us a bit about your team. We'll follow up within two business days.